rac-1-[6-Hydroxy-4-(4-methoxyphenyl)-3,6-dimethyl-4,5,6,7-tetrahydro-2H-indazol-5-yl]ethanone

rac-1-[6-Hydroxy-4-(4-methoxyphenyl)-3,6-dimethyl-4,5,6,7-tetrahydro-2H-indazol-5-yl]ethanone

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The title compound, C18H22N2O3, represents a (4S,5R,6S)-stereoisomer, crystallizing as a racemate in a centrosymmetric space group.The six-membered aliphatic ring adopts a half-chair conformation, with Goldenseal the hydroxy- and acetyl-substituted C atoms deviating by 0.458 (2) and −0.366 (2) Å, respectively, from the plane defined by other four ring atoms.

The pyrazole ring is essentially planar [r.m.s deviation = 0.004 (2) Å].

In the crystal, 4 Door Fridge the molecules are linked into chains along the b axis by N—H.N hydrogen bonds.The chains are linked by O—H.N hydrogen bonds into layers parallel to the bc plane.